Oddly you never hear anyone discuss the possible conflicts of interest that this educational material from Novo Nordisk, the makers of Ozempic and Wegovy, have funded
Symptoms of Vitamin B12 Overdose The symptoms of excessive Vitamin B12 are very similar to the symptoms exhibited if you are deficient
Natural amylin: the forgotten satiety hormone What amylin is: 37-amino acid peptide hormone Co-secreted with insulin from pancreatic beta cells Released in response to meals (nutrient intake) Discovered in 1987 (relatively recent) Named "amylin" for amyloid-like structure Amylin's natural functions: Where amylin acts: Area postrema (brainstem) - primary satiety effect Nucleus accumbens (brain) - reward/feeding behavior Stomach smooth muscle - direct gastric slowing Pancreas alpha cells - glucagon suppression Amylin vs insulin (complementary hormones): Both secreted together from beta cells Insulin: Handles glucose uptake Amylin: Controls meal size and gastric emptying Work synergistically to regulate feeding and metabolism Learn fundamentals at SeekPeptides - explore what are peptides , how peptides work , and peptides for weight loss
Mounjaro is indicated for adults with a body mass index (BMI) of 30 kg/m or greater , or 27 kg/m or greater in the presence of at least one weight-related comorbid condition such as hypertension, dyslipidaemia, obstructive sleep apnoea, or cardiovascular disease
Note: In this area, most studies to date have been small or in animals, so more long-term research in human subjects is needed
While their efficacy for many patients who take them is remarkable, understanding their potential side effects is vital for patients considering or currently using these medications
