Patients inject the medication into fatty tissue, typically in the abdomen, thigh, or upper arm
The selection of specific sites depends on factors including skin thickness, local blood flow, hair density, and the potential for the patch to be dislodged by clothing or physical activity
They are significantly larger than the molecules in a typical nicotine or birth control patch, making it very difficult for them to pass through the skin's protective outer layer and into the bloodstream in a therapeutic dose
Its also not FDA approved, since its considered a supplement, not a medication
Never apply patches over broken, irritated, or diseased skin
Patients should always follow the specific instructions provided with any licensed transdermal medication, as optimal sites will vary depending on the formulation's characteristics and the manufacturer's validated application protocols as detailed in the product's Summary of Product Characteristics (SmPC) and Patient Information Leaflet (PIL)