Ozempic is a brand name for semaglutide, a GLP-1 receptor agonist, and is an FDA-approved product
Tirzepatide vs semaglutide 2.4 mg in non-diabetic obesity SURMOUNT-5 direct head-to-head, -20.2% vs -13.7% at 72 weeks: Aronne NEJM 2025
They are not FDA-approved and may lack the uniform quality and safety standards of brand-name drugs like Ozempic or Wegovy
The obesity rate dropped to 37% of U.S
In rare cases, serious side effects such as pancreatitis (inflammation of the pancreas), gallbladder problems, severe abdominal pain, or signs of an allergic reaction can also require discontinuation
"However, at the time of study conduct, limited availability of semaglutide in China made its inclusion as a comparator unfeasible." For now, the researchers said side-by-side consideration with the Phase 3 SUSTAIN-China study of semaglutide might offer some insight