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Using delta sleep-inducing peptide (DSIP), a vital sleep peptide, it interacts with receptors in the hypothalamus and the central nervous system to regulate motor functions and balance cortisol levels, which are essential for managing stress, promoting relaxation, and reducing inflammation

Subsequent studies established its identity as a member of the cullin family (9), with its encoding gene localized to chromosome 11q22-23 (7)

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However, there is no established evidence supporting any cognitive or neurological effects in humans

The overall survival of patients in the high-risk group was significantly worse than that of patients in the low-risk group

Most patients need ongoing follow-up