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BENEFITS/ CLINICAL TRIALS Melanotan I is a linear peptide that primarily binds with high affinity and selectivity to the Melanocortin 1 Receptor (MC1R) found on melanocytes (skin pigment cells)

The medication works by binding to GLP-1 and GIP receptors in your brain's appetite center, signaling fullness earlier than usual

Ozempic (semaglutide) is a GLP-1 receptor agonist licensed in the UK for type 2 diabetes that typically reduces appetite by mimicking natural hunger-regulating hormones

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Trial: Dapiglutide, a dual GLP-1 and GLP-2 receptor agonist, for obesity: a randomised, double-blind, placebo-controlled parallel-group, proof-of-concept trial

Castelli V, dAngelo M, Quintiliani M, Benedetti E, Cifone MG, Cimini A (2021) The emerging role of probiotics in neurodegenerative diseases: new hope for Parkinsons disease