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Vernero M, De Blasio F, Ribaldone DG, Bugianesi E, Pellicano R, Saracco GM, et al

Abstract With the increasing prevalence of alcohol-related diseases, expanding our understanding of the toxic effects of excessive alcohol consumption is critical for prevention and treatment of metabolic and inflammatory pathology

Nature 509 (7498), 105109

By inhibiting NNMT, 5-Amino-1MQ prevents the methylation of nicotinamide, allowing more substrate to enter the NAD+ salvage pathway

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