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We previously reported significantly increased ROS levels in the sera and livers of HCV-infected tree shrew, which is an emerging small animal model of the Tupaiidae family susceptible to HCV infection 56,57

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The honest answer is that DSIPs own pharmacology a plasma half-life measured in minutes in every animal species tested, and reported effects that were explicitly not dose-proportional is the reason no consensus dose ever emerged, and why the numbers circulating online bear little resemblance to the numbers in the studies

Six normal subjects injected with 25 nmol/kg DSIP once in the morning showed a significant increase in total sleep for the next 2 hours (median increase of 59%)

PMID 18709899

The San Francisco Standard