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Pathogenesis of non-alcoholic fatty liver disease in children and adolescence: from two hit theory to multiple hit model

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DOI: 10.1371/journal.pone.0138911

Prescribers should document that any mild ALT elevation at baseline predates ipamorelin use and establish a clear threshold (e.g., 2 times baseline or 2 times the upper limit of normal, whichever is lower) that would trigger hold-and-reassess

Lower the weight slowly over 3 to 5 seconds