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At nearly 5000 Da, it approaches the upper limit of what intranasal delivery can effectively handle

Perhaps most remarkably, cerebrolysin shifts microglial phenotype from the pro-inflammatory M1 state to the anti-inflammatory M2 state

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Further analysis suggested that the peptide may have increased the ratio of Bcl-2/Bax, and potentially decreased cleaved caspase-3 and PARP levels, two markers of cell death

10.1038/s41467-020-19871-x