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In this case, the mechanism of down-regulation is linked to promoter methylation (Scalise et al., 2012

Glutathione molecules have their own life cycle. As glutathione (GSH) is utilized and oxidized, it becomes oxidized glutathione (GSSG)

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GLP-1 medications are currently considered long-term treatments

Other corticosteroids (risk of additive systemic effects)

Quality assessment The methodological quality of the included studies was evaluated using the Newcastle-Ottawa Scale (NOS) [24], which assesses three domains: selection of study participants, comparability between groups, and the ascertainment of exposure or outcomes, with a maximum achievable score of 9 points