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They are also synthesized by neurons and are co-stored and/or released together with other neuropeptides

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not approved Tirzepatide (Zepbound) Approved (Zepbound, Mounjaro) Semaglutide alone (Wegovy) Approved (Wegovy, Ozempic) Cagrilintide alone Investigational Feature Head-to-head data CagriSema Did not meet non-inferiority vs tirzepatide at 84 wks (Reuters Feb 2026) Tirzepatide (Zepbound) Semaglutide alone (Wegovy) Cagrilintide alone These compounds are not interchangeable

Since this is a new delivery platform of existing drugs rather than a new drug, the regulatory bodies in many jurisdictions typically have alternative, shorter approval pathways available to drug sponsors that do not require the standard Phase I-III clinical trials for a new drug application

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