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After an average follow-up of 4 years, the relative risk of probable dementia for CE plus MPA versus placebo was 2.05 (95 percent CI, 1.21-3.48)

Methods: Sixty rats were randomly assigned into six groups: Group I (Control), Group II (PPA-treated), Group III (Control-GABA), Group IV (Control-Combination), Group V (PPA-GABA), and Group VI (PPA-Combination)

Aim for 25-38 g of fiber daily, increasing intake gradually to minimize gastrointestinal side effects

Safety and Side Effects Common Side Effects While GLP-1 receptor agonists are generally well-tolerated, they can lead to side effects, particularly gastrointestinal issues

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J Endocrinol 207:343353