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L-alanylglutamine inhibits signaling proteins that activate protein degradation, but does not affect proteins that activate protein synthesis after an acute resistance exercise

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mean values indicated

Wagle, N

The most relevant glutamine-producing tissue is the muscle mass, accounting for about 90% of all glutamine synthesized

Effects are likely mediated via circumventricular organs (brain regions lacking a complete blood-brain barrier) and vagal afferent pathways, with limited direct penetration