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[1] [2] The incidence of these effects increased with higher doses, consistent with the dose-dependent pharmacology of GLP-1 receptor agonists as a class

The FDA label for Increlex explicitly warns of hypoglycaemia, intracranial hypertension, and slipped capital femoral epiphysis as serious adverse events

Critically, it does not bind to the growth hormone receptor and does not raise IGF-1 levels.[1] This means its effects stay localized to fat metabolism, making it a much more targeted option than full hGH therapy

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Les attentes doivent etre alignees sur la realite d'une litterature essentiellement preclinique et de quelques series pilotes anciennes : phenotypes coherents mais pas spectaculaires, reponse individuelle variable, necessite de protocoles bien construits pour observer quelque chose.