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Therefore, Table 1 also includes preclinical and cross-disease translational evidence with mechanistic relevance

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FDA-approved GLP-1/GIP medications for weight loss and type 2 diabetes, including Ozempic, Wegovy, Zepbound, and Mounjaro, may also be eligible for coverage

When testing each drug type separately, we estimate the effect of the SNP on BMI % to be larger in tirzepatide (effect = 0.95%) than semaglutide (effect = 0.51%), although the 95% confidence intervals were overlapping (Extended Data Fig