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This class of compounds binds to key receptors in the brain, pancreas, and gastrointestinal (GI) tract, instigating several biological reactions: Enhances insulin secretion Slows gastric emptying Increases -cell proliferation Reduces glucagon release Mitigates hunger signaling These actions combine to regulate appetite, food intake, and the physical feeling of fullness (satiety)
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doi: 10.3389/fphar.2020.00967 Received 17 March 2020 Accepted 15 June 2020 Published 30 June 2020 Volume 11 - 2020 Edited by Keizo Kanasaki, Shimane University, Japan Reviewed by Shinji Kume, Shiga University of Medical Science, Japan
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