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[PMC free article: PMC9659651] [PubMed: 36117266] 42

If it persists, seek advice from your healthcare professional

This combined receptor activity has produced remarkable outcomes in early human studies, where participants achieved average body weight reductions exceeding 24% within roughly a year at the highest tested doses

Finally, it is not uncommon to find patients with obesity and diminished mobility to have both an increase in body fat and decrease in lean (muscle) mass [58]

What skin-related side effects have been reported

Glucagon increases energy use and fat burning