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While the original 2002 paper in the Journal of Cosmetic Dermatology is referenced throughout current dermatology literature (including Pickart & Margolina, 2018), direct access is available through Wiley Online Library

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Stir with a clean utensil and wait for 30 minutes or until the powders have completely dissolved

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Insert at 90 degrees (straight in) when there is sufficient tissue depth and no pinch is needed

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It is thought to reduce the production of prostaglandins (chemicals that cause inflammation) in the brain and to lower fever through its action on heat-regulating centers in the brain but the precise mechanism remains unclear

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The MRI images after normalization were segmented into gray matter, white matter, cerebrospinal fluid, and other compartments using a maximum likelihood mixed model algorithm, a modified version of the clustering algorithm

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