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Financial support and sponsorship This work was supported by funds from the following institutions: Institut National de la Sant et de la Recherche Mdicale - INSERM, Fondation pour la Recherche Mdicale, the Conseil Rgional dAquitaine, Fondation ARC pour la Recherche sur le Cancer, Ligue Contre le Cancer - Gironde, SIRIC-BRIO, Institut Europen de Chimie et Biologie, and University of Bordeaux

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