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What is retatrutide and how much weight can it cause people to lose
After 26 weeks, the levels of hs-CRP and endothelin-1 decreased (27.5% and 18.75%, respectively) in the exenatide arm whereas the levels of fibrinogen, monocyte chemoattractant protein-1, leptin and endothelin-1 increased in the insulin glargine arm (13.4%, 30.2%, 47.5%, and 80%, respectively) [45]
doi: 10.1007/s00125-023-06053-9
Marketed as Mounjaro for type 2 diabetes and Zepbound for weight management, tirzepatide represents a significant advancement in peptide therapeutics[3]
Last reviewed: May 25, 2026 Last updated: May 25, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations