GLP-1 agonists like semaglutide and tirzepatide are peptide hormones that activate GLP-1 receptors on pancreatic and gastrointestinal cells
Retatrutide is an investigational triple agonist targeting GLP-1, GIP, and glucagon receptors, producing strong appetite suppression and delayed gastric emptying
Sharma went off the drug after reaching her goal weight in November last year, but her appetite resurfaced in late February, and she has regained about half of it back
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People are increasingly interested in microdosing GLP-1 medications because even at the lowest therapeutic doses, these medications appear to influence multiple metabolic pathways
The patients who do best usually treat this period as active medical follow-up, not a passive prescription refill