Dihexa (PNB-0408) (2-4mg/kg;b.wt.;16 weeks) is promising candidates for adjunct therapies to promote limb functional recovery after surgical nerve repair, and have implications in peripheral nerve injury and limb transplantation [8]
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Vitamin E can also inhibit activation of protein kinase C [173,174], which can block GS expression [175], leading to the disinhibition of GS and ultimately the reduction of excitotoxicity