Similarly, the dual GLP-1R and GIP agonist tirzepatide promoted the intake of standard rodent chow at the expense of a high-fat diet in mice, suggesting a preferential shift toward less energy-dense foods (Geisler et al., 2023)
Care gap
To better understand the human side of the GLP-1 divide, The Health Management Academy surveyed 1,827 Americans in November 2025 to capture the real-world impact of the GLP-1 divide, highlighting the emotional, social, and financial toll it takes across different incomes and between men and women
The vast majority of them 129 million qualify to take it for weight loss based on their BMI and weight-related complications like high blood pressure
Choice 2 Stop taking Ozempic and lose all my weight loss progress
For some, they feel like a breakthrough after years of struggling with blood sugar issues, metabolic dysfunction, or weight gain despite dieting and other approaches