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However, evidence for broader populations beyond PCOS remains limited

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The researchers found that among 334 patients receiving oral semaglutide at a 50 mg dose, three to nine patients experienced altered skin sensations including dysesthesias, hyperesthesia, neuralgia, pain of skin, paresthesia, sensitive skin, and skin burning sensation

These symptoms are different from mild irritation because they tend to intensify, expand, or come with whole-body symptoms