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5 Briefly, the conversion of dietary precursors into TMA involves four enzymatic pathways, including the choline-utilizing TMA lyase system (CutC/D), the carnitine Rieske-type oxygenase/reductase system (CntA/B), betaine reductase, and TMAO reductase

Compared to HCs, these analyses revealed that 18 pathways were significantly altered in LC patients ( Figure 3A )

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doi:10.1016/j.eclinm.2024.103029 25.Ayoub M, Chela H, Amin N, et al

Persistent fatigue induced by interferon-alpha: a novel, inflammation-based, proxy model of chronic fatigue syndrome

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