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Excess free radicals are generated during detoxification and ME-3s ability to increase total antioxidant activity (TAA) means it will help protect the liver. 6) Balancing inflammation: Lactobacillus fermentum ME-3 has been shown to reduce levels of several key pro-inflammatory markers such as high sensitivity C-reactive protein (hs-CRP) and interleukin 6 (IL-6), and it is also capable of stimulating production of the peptide adiponectin and of reducing levels of glycated hemoglobin or HbA1c. Since inflammation has been shown to be a major contributing factor in most of todays chronic degenerative diseases, a substance that balances levels of inflammation can be a substance that helps to improve overall health