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She was on the medication for 16 weeks before she began to taper, cutting down over a period of six weeks

71 These modulators can potentially provide more selective activation of the receptor, reducing adverse effects and improving efficacy

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A few participants with a BMI above 27 kg/m participated, but only if they had an additional weight-related health issue, such as hypertension or hyperlipidemia

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The most important known patterns for the therapeutic effects of GIP agonism as well as antagonism in preventing obesity and in reducing body weight are summarized in Table 1 (49)