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The Hallmarks of Aging: Why Longevity Matters In 2013, scientists identified nine biological hallmarks of aging, including: Genomic instability Telomere attrition Mitochondrial dysfunction Chronic inflammation (or inflammaging) Each hallmark contributes to the functional decline associated with aging

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The GIPR rs1800437, GLP1R rs6923761, FTO rs9939609, and MC4R rs17782313 variants reveal predispositions in peptide signaling and metabolic regulation

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