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Melatonin analogs UCM 976, UCM 1032, UCM 1033, UCM 1037) that target membrane receptors MT1 and MT2 showed an ability to inhibit the proliferation of DX3 melanoma cells and MCF-7 breast cancer cells, and MDA-MB231 in a dose- and time-dependent manner in viability assays

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Allow peptide vials to reach room temperature before opening to prevent condensation that could affect peptide stability

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This prevents overlapping receptor activation that could intensify side effects beyond what either drug would produce alone

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