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If you miss a scheduled injection or skip doses, the medication remains usable until the 28-day mark passes, provided storage conditions remain correct

It is safe, extensively studied in humans for decades without any adverse effects

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Mol Ecol 28(13):31973207 Tanase DM, Gosav EM, Neculae E, Costea CF, Ciocoiu M, Hurjui LL, Tarniceriu CC, Floria M (2020) Hypothyroidism-induced nonalcoholic fatty liver disease (HIN): mechanisms and emerging therapeutic options

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Prolonged vitamin B12 deficiency can also lead to irreversible damage to the nervous system