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Participant selection will be based on the inclusion and exclusion criteria described below

J Clin Endocrinol Metab (2020) 105:e37426

This randomized phase 2a #ClinicalTrial demonstrates that TPN171H, a potent and selective PDE5 inhibitor, significantly reduces pulmonary vascular resistance and improves acute hemodynamics in patients with #PulmonaryArterialHypertension (PAH), establishing it as a promising and well-tolerated oral therapeutic candidate for managing PAH

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