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Dose-dependence, surface chemistry, and renal clearance or RES clearance critically influence both therapeutic efficacy and potential off-target effects

Results Body weight, fat mass, and cecal mass As expected, obese mice (maintained on an HFD followed by WD) had significantly higher body weights than mice continuously maintained on LD

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How to Use Each Compound: Administration and Dosing These two compounds are used very differently because they work through different mechanisms