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Indeed, ALT telomeres have a relaxed telomeric chromatin configuration (compared to telomerase positive and normal cells) making them more susceptible to DNA damage and telomere elongation through ALT (Lin et al 2021

The Balanced View BPC-157 is a defined 15-residue synthetic peptide with a substantial preclinical literature

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Morphologically, the most important morphological changes of ferroptosis are mitochondria, including mitochondrial contraction, electron-dense mass formation under ultrastructure, reduction or disappearance of mitochondrial cristae, changes in membrane potential, and rupture of mitochondria outer membrane (Vanden Berghe et al., 2014)

Metabolite extraction and MS analysis Metabolites were extracted from 5 10 6 20 10 6 cells by modified Folch extraction (chloroform, methanol and water, 8:4:3)