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There's now a study that looked at this mechanistically

Figure 5 3.5.6 Potential clinical value Given their multitargeted mechanisms and low toxicity profiles, ITCs are actively explored in clinical settings as chemopreventive or adjunct therapeutic agents (128)

Any temperature excursion above 8C accelerates peptide aggregation

doi: 10.1016/j.bbadis.2012.10.005 69 HendersonNCArnoldTDKatamuraYGiacominiMMRodriguezJDMcCartyJHet al

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This interaction might lead to intermittent growth hormone emissions despite Sermorelin's truncated amino acid structure