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The increase in the secretion of inflammatory mediators and the reduction of anti-inflammatory factors will further aggravate the immune response, leading to more serious disease progression [17], an effect confirmed by a significantly imbalanced Th17/Treg cell ratio in AR patients [18]

10.1007/s00726-009-0269-0 94

Am J Respir Cell Mol Biol

Although these are the most relevant questions clinically, there is still little consensus as to how much, how often and for how long to administer IVC to oncology patients