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[9] Visual disturbances have been reported in patients with Leber hereditary optic neuropathy, and rapid B12 administration may precipitate optic nerve atrophy in this genetically predisposed population, mandating extreme caution or alternative therapy

This is probably the question researchers ask most frequently

Reported side effects are infrequent and mild: Mild headache or dizziness following administration

"I voted yes because it's time to put this decision back in the hands of the patient, the physician and the pharmacist," said David Pope, chief pharmacy officer of Xifin Pharmacy Solutions

found that epithalon can, when administered to both elderly monkeys and people, modulate the functional state of the pineal gland, which secretes melatonin to control the circadian cycle and wakefulness [8]

Ans : Excess use may lead to mild side effects