Modulation of the brain-gut axis and the NO pathway
Inflammation and oxidative stress inhibition: GLP-1RA protects myocardial and renal cells from damage caused by energy metabolism disorders by inhibiting the NF - B pathway and NADPH oxidase activity, reducing the production of inflammatory factors such as IL-6, TNF - , and reactive oxygen species (ROS)
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Luciferin detection reagent (LDR) (100 l) was added to all wells, briefly shaken and incubated for 15 min at room temperature and the luminescence measured using microplate imager (BioTek Cytation3)
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Dolgacheva LP, Zinchenko VP, Goncharov NV (2022) Molecular and cellular interactions in pathogenesis of sporadic parkinson disease