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RNA-binding proteins, particularly TDP-43, play a key role in protein aggregation
Unlike older peptides, CJC-1295 is engineered to have a longer half-life due to its ability to bind to albumin
For patients with chronic kidney disease or heart failure, SGLT2 inhibitors are generally prioritised, with GLP-1 receptor agonists as complementary therapy where appropriate
The main distinction is their size
The mechanism of action involves mimicking two naturally occurring incretin hormones that regulate blood glucose levels and appetite
The two receptor systems are biologically independent at the molecular level
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