European Medicines Agency decision P/0336/2024 on retatrutide paediatric investigation plan
Potential side effects and management While compounded GLP-1 is generally well-tolerated, there are side effects to be aware of
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Proteins that are up-regulated in tumor vessels alter vascular function, and may constitute new targets for therapy as discussed further below
In this nationwide cohort of more than 27,000 individuals with asthma and also overweight, obesity or T2DM, use of GLP-1 drugs was associated with significant reductions in exacerbation burden as well as reliever use, exposure to inhaled corticosteroids and pneumonia events, irrespective of whether the drugs were being used to treat obesity or T2DM, the authors concluded
Weight gain is the second major side effect