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For people using these drugs for blood sugar control, the loss of effectiveness carries much more immediate risk than for someone who might only see slower or less weight loss

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Thus, drugs that mimic the action of GLP-1, known generally as GLP-1 receptor agonists, are widely used in the management of T2D and obesity, which as outlined above are both closely linked to CKD

[DOI] [PubMed] [Google Scholar] 40.Rosenstock J, Kahn SE, Johansen OE, Zinman B, Espeland MA, Woerle HJ, Pfarr E, Keller A, Mattheus M, Baanstra D, Meinicke T, George JT, von Eynatten M, McGuire DK, Marx N, CAROLINA Investigators Effect of linagliptin vs glimepiride on major adverse cardiovascular outcomes in patients with type 2 diabetes: the CAROLINA Randomized Clinical Trial

The vitamin is crucial for myelin synthesis, the protective sheath surrounding nerve fibres