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As of 2021, the International Diabetes Federation (IDF) estimates that approximately 537 million adults have diabetes globally, and this number is forecast to rise to 783 million by 2045
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This regulation promotes BRCA progression by enhancing cell proliferation through cross-talk with signaling pathways like RAS-RAF-MEK and PI3K-AKT, independent of mTORC1
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During follow-up, 169 patients (4.39%) in the GLP-1RA cohort and 234 patients (6.07%) in the DPP-4i cohort experienced the primary composite outcome of ruptured aortic aneurysm or aortic dissection requiring surgical or endovascular repair