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Controlling the arrangement of these biomolecules is therefore of great interest when striving to mimic native tissues [47,48]

World J Gastroenterol, 2018

The most frequently used treatment relies on the combination of several immunosuppressants such as corticosteroids, leflunomide, and standard disease-modifying antirheumatic drugs (DMARDs) like methotrexate (MTX) 11 to address joint inflammation

373 In fact, when BMSCs are exposed to exendin-4, the expression of genes related to bone development factors such as Runx and Osterix, as well as genes responsible for producing the bone matrix such as Balp and Bglap, is upregulated

Notably, the SNX1-SNX2 heterodimer produces heterogeneous structures, including spherical vesicles, recapitulating in vivo observations

They work by optimizing existing follicles, not creating new ones