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5 The bioactive forms, GLP-1(737) and most abundantly, GLP-1(736)NH 2 , are inactivated by dipeptidyl peptidase-4 (DPP-4)

If you experience severe abdominal pain, persistent vomiting, or signs of dehydration at any point, contact your provider as soon as you can

The 72-hour minimum gap between any two injections prevents plasma drug levels from stacking to supratherapeutic concentrations, which increases the risk of GI adverse events (nausea, vomiting, diarrhea) that are already the most common reason patients discontinue GLP-1 therapy

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While your natural GLP-1 is broken down in minutes, some types of these medications can work for days, leading to sustained appetite suppression and improved blood sugar control (1)