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Reduced ability of HDL to stimulate NO production from endothelial cells and decreased vasorelaxation properties are reported for T2DM (887,888), T1DM (889), mild chronic kidney disease (CKD) (890), and rare forms of autoimmunity (ALPS) (891)

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The results showed that FA injection markedly enhanced the secretion of TNF- and IL-1 in the tubular epithelium, together with the increased infiltration of macrophage in the interstitial space, whereas LA supplementation downregulated the levels of these molecules

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The reconstitution process requires different considerations