[10] [6] In the UK, NICE guidance (TA875) recommends Wegovy only within specialist weight management services for adults with a body mass index (BMI) of 35 kg/m or above (or lower thresholds for certain ethnic groups), or 30 kg/m or above with weight-related complications
While true allergic reactions to B12 are exceptionally rare, they can present with various symptoms that might include joint discomfort alongside other systemic manifestations
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GIP may also influence fat metabolism and bone health, though these effects are still being investigated in humans
Shafipour points out that the body can adapt to medications, so the drugs can become less effective over time for weight loss and blood sugar control