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Tolerance (i.e., need for increased amounts or diminished effect with continued use of the same amount)* Experiencing withdrawal (opioid withdrawal syndrome) or taking opioids (or a closely related substance) to relieve or avoid withdrawal symptoms.* *Patients who are taking opioids as prescribed by a healthcare provider may experience tolerance and withdrawal, but in that case, do not have opioid use disorder

The effect on the Medicaid program is expected to be limited to copayments that Medicaid may make on behalf of Medicaid recipients who are also Medicare beneficiaries

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[DOI] [PubMed] [Google Scholar] 48.Jiang T., Xu G., Chen G., Zheng Y., He B., Gu Z

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