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3.2 Neurological damage and psychiatric symptoms The neurological effects of cocaine include diffuse leukoencephalopathy, which is characterized by vasospasms, cerebral ischemia, and posterior reversible leukoencephalopathy (Rowbotham and Lowenstein, 1990

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In the Phase III NefIgArd trial, patients treated with Tarpeyo saw significantly better kidney function, as measured by the estimated glomerular filtration rate (eGFR) versus placebo after nine months on the drug and 15 months of follow-up