When deficient, animals can have reduced appetite and growth rates, ill thrift, infertility, and reduced wool and milk production
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Too high levels caused by either excess ROS production or impaired detoxification lead to oxidative stress, elevated tissue damage, and pathophysiological stalling 14,15 , whilst too low levels impede cellular and molecular processes of wound healing which are dependent on ROS-mediated signal transduction 7 ultimately leading to the formation of chronic wounds
A-PW, YT, S-XG, and NL contributed significantly to the analysis and manuscript preparation
[PMC free article: PMC441650] [PubMed: 13332064] 270