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Some patients need closer blood pressure monitoring while taking tirzepatide

But only participants with obesity ended up drinking significantly less than their peers who received a placebo

[19] It is available on NHS prescription for adults with a BMI 28 kg/m (with risk factors) or 30 kg/m, alongside dietary and lifestyle measures

The SURMOUNT trials showed tirzepatide at 15 mg achieving 15% to 21% weight loss by week 72, compared to semaglutide at 2.4 mg achieving approximately 15% by week 68

But the evidence shows that a complete stoppage will undo a lot of the benefits you accrued over time. Ali also points out that new medications are coming, too

During the first week, its normal to experience a gradual reduction in hunger and an increase in feelings of fullness, but the appetite-suppressing effects may take some time to become fully apparent