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Charting differentially methylated regions in cancer with Rocker-meth Commun Biol 4, 1249 (2021)

In the early stage of tumor colonization or growth, activated immune cells contribute to a tumor-suppressive inflammatory microenvironment that hinders tumor development, whereas long-term persistent antigenic stimulation, the activation of immunosuppressive cells and metabolic stress prompt the tumor to escape from the surveillance of the immune system and continue to grow, which is known as immune escape of the tumor (70,71)

Tripolt NJ, Leber B, Triebl A, Kfeler H, Stadlbauer V, Sourij H

Morphologically, the majority of contacts between the GHRH perikarya and endogenous opiates were enkephalinergic while only few dynorphin- and endorphin-GHRH interactions were detected

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